HORDB

ID: hor004961
Uniprot ID: P69105
Protein name: Gonadoliberin-3
Gene name: gnrh3
Organism: Oncorhynchus keta (Chum salmon) (Salmo keta)
Family: GnRH family
Source: animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Oncorhynchus (genus), Salmoninae (subfamily), Salmonidae (family), Salmoniformes (order), Protacanthopterygii, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Function: Stimulates the secretion of gonadotropins, luteinizing and follicle-stimulating hormones.
Mechanism: NA
Cross BBB: NO
Target: NA
Target Unid: NA
IC50: NA
EC50: NA
ED50: NA
kd: NA
Half life: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor004961_AF2.pdb

hor004961_ESM.pdb

Mass:	139106	Formula:	C60H75N15O14
Absent amino acids:	ACDEFIKMNRTV	Common amino acids:	GW
pI:	7.54	Basic residues:	1
Polar residues:	4	Hydrophobic residues:	3
Hydrophobicity:	-92	Boman Index:	-228
Half-Life:	0.8 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	39
Instability Index:	4157	Extinction Coefficient cystines:	12490
Absorbance 280nm:	1387.78